My Experience Essay

As I reflect upon my life I will describe facts and events believed to have contributed to the person I am today. I like how Merriam Webster’s online dictionary explains experience as something personally encountered, undergone, or lived through. I have encountered difficulties, circumstances, and triumphs that have helped me to grow as a person. I am pursuing a higher education as my future goal. In this paper, I will apply theories from Adult Development and Life Assessment in my explanation of challenges I have faced during childhood to adulthood. I was born in Chicago, one of six girls and the middle child of twelve. As early as I can remember we worked as a group. We played together and we worked in the garden that my parents made in our back yard. I hated the garden because every time I wanted to go play, I first had pick vegetables out of the garden. I didn’t understand at the time that my parents used the garden to help feed our large family. My dad always worked two jobs; his primary employment was with a company called Central Soya. When my father retired from there we moved to Alabama because the cost of living was cheaper. We didn’t have a lot of material things like clothes and shoes. My mother would buy tennis shoes from the grocery store and my brothers would be so embarrassed because their friends saw them trying on the shoes in the store. I can remember my dad making me a pair of pants for school; I thought they were the prettiest pair of pants I had ever seen. It was cheaper to make a pair of pants than to buy them. My parents cut corners any way they could. We may not have had material things but what we did have was love and lots of talent. Not real talent but talent that’s appreciated in a family. On rainy days mom and dad would have us put on a talent show. It was so much fun that we kept the tradition even until adulthood. On birthdays and holidays we would use our talents to entertain mom and dad. Birthdays were especially special because my dad would make me a birthday cake. He was a really good cook and everyone in the neighborhood wanted a piece of his cake. My sixteenth birthday marked a significant shift in my life. I became pregnant and it was one of the biggest mistakes that started a downward spiral in my life. I hung out with older girls that had children. They were into partying and so called having a good time. Our environment plays a huge role in how we develop, what pathways are open to us, and which are closed (Witt, G.A., & Mossler, R. A. (2010). I feel like the environment that I chose to be in led to early exploration of drugs and alcohol. I could see myself going in the wrong direction with more terrible consequences if I didn’t make a change. I stopped hanging out and got my first job. It was on a military base in the mess hall. I met a soldier and we got married on our way to work one day when I was twenty one years old. We dated for four months then he went overseas for a year. We married a year later after he returned to the states. Being married was a challenge because he was abusive physically, verbally, and mentally. I had listened to his insults for so long that they became part of my own vocabulary. I began to think that maybe he was right, maybe if I could cook, clean, dress or talk better it would fix our problems. In our text Freud believed that the mind uses defense mechanism to protect itself from severe distress. In the beginning I rationalized everything he did, in rationalization: we look for an acceptable reason to justify our thinking or behavior (Witt & Mossler 2010). I got involved in church and accepted the Lord Jesus Christ as my savior. As a result I think a lot of the abusive behavior was able to continue because I simply forgave, thinking it was the Christian thing to do. According to Haan (1977), coping strategies involve choice and purposive behavior, are oriented toward reality, involve differentiated thinking that integrates conscious and preconscious aspects, and permit affective satisfaction in an open, ordered, and tempered way (Psychology and Aging 2000 ). It came to a point after seventeen years of abuse I couldn’t take it anymore. I had done all that I could physically to have a successful marriage but it wasn’t working out for me. I had to face the cruel reality that my marriage was over. Finally I filed for a divorce, which was one of the scariest things I have ever done in my life. Going through the divorce gave me a sense of freedom and strength that I had never experienced in my marriage. Getting a divorced was the best thing I could have done for myself. It started me on a journey to find out what I want out of life for myself. It marked a new beginning to a better, brighter future in my life. I was free to make my own decisions that impact my life. One of those decisions was returning to school for a degree. I really want to be an example to my daughter and her children that education is the key to success, and you are never too old to be successful in life. I must admit that I was very afraid of returning to school because I thought that I would not be successful. I thought that I wouldn’t be able to remember things or comprehend how to do the work. Some researchers contend that intellectual functioning is a process of irreversible decline. However, most scholars agree that intelligence either remains relatively stable through the adult years, with substantial intellectual changes occurring only very late in life, or that intelligence declines in some respects, remains stable in others, and may even increase in some functions, depending on a person’s educational level, life experiences, and overall health (Intelligence and Aging 2007). I am now encouraged to pursue my education. I’m not too old, I plan to finish my courses and earn my degree. My goal is to apply for higher positions that require a degree. There will be many opportunities open to me once I earn my degree in my field of study. In conclusion, I have shared different experiences that have influenced my personal life. I have used theories from this class to support my experiences and I have shared my future plans to achieve my academic goals. Every lesson I complete moves me one step closer to my goal. References Intelligence and Aging (2007) Learning in Adulthood: A Comprehensive Guide. Retrieved from http://www.credoreference.com/entry/wileyla/intelligence-and-aging Witt, G. A., Mossler, R.A., (2010). Adult Development Retrieved from http://content.ashford. edu /AUPYS202.10.1 Vief, G. L., Diehl, M., (2000) Cognitive complexity and cognitive-affective integration. Psychology and Aging. Vol.15 (3) US: American Psychological Association pp. 490 -504.doi:10.1037/0882-7974.15.3.490

Merill Lynch

Supernova refers to a new way to manage client relationships that originated in one of Merill Lynch’s Indianapolis offices. The first preparation before the process of Supernova was establishing relationship with client in the area of client satisfaction; The frequency and quality of contact Rapid response to problems Attention to details The changes required to implement the Supernova process includes Maintaining minimum contact time Reducing the number of customers Folder system Through the Supernova process, FAs must maintain minimum contact time which is the 12-4-2 which is 12 monthly contacts of which 4 were portfolio reviews and 2 were face-to-face meetings. Besides that, FAs would have to segment the number of customers. They have to rank their clients according to revenue generation, assets, favour of doing business with and etc. Most of them decided to reduce their clients to 200, important family or business associates, clients described as necessary. The FAs would have to implement Folder system that was done by the client associates. This is to provide systematic approach in FAs duties which is consistent with the Supernova process. As for the company, they may need to increase workforce at the Financial Advisory Center as many less promising clients are being let go by the FAs. There are several risks in this Supernova process. The first risk is that the FAs jeopardize the Supernova â€Å"brand† in that their clients would not be as satisfied as those of complete adopters. Second, Supernova advocates agreed that a failure to fully adopt the program meant that its benefits for FAs such as improved compensation and quality of work life would not be enjoyed. Third, when service promises were made to clients by FAs who intended to fully adopt Supernova but never completely implemented the program. Fourth, many traditional FAs associated the new approach (gathering and allocation) with Supernova. Fifth, the FAs felt that the CRM software that was used no doubt is the best out there but it’s a complex solution which may be difficult to be used by the FAs. The potential benefits in the Supernova process includes customer retention improved communication better organized FAs The customer retention is essential towards both FAs and the company. Once the customers are being identified, they are kept abreast and updated by their FAs. This served as a platform for both the customers and the FAs to have better bonding. The communication between the FAs and the customers improved as customers would definitely be sure to receive a call at least 12 calls for a year. Customers would also receive quick response to any problem that may arise. The FAs learnt to be more organized and be systematic through the folder process which is consistent to the implemented 12-4-2 program.

Response to “We Should Cherish Our Children’s Freedom to Think” by Kie Ho

We read the article, â€Å"We Should Cherish Our Children’s Freedom to Think† last week. The author Kie Ho uses his own experiences about his son’s thought and many examples to prove his point. He thinks that public education certainly is not perfect in America, but it is a great deal better than any other country. Children should be more liberal thinking, writing and imagining, rather than comply with the rules or follow the prescribed order of their parents and the execution of what adults say. Children’s creativity brings inspiration to adults, improves the act of education and makes the change to the world.It is also can make children have a better future. The system of education is not perfect; it is difficult for the children to freely to think, write and create when they began to study the knowledge from the school for a long time, because school teaches the knowledge that is scientific and rigorous. The knowledge is the system and it needs to be au dited and modified. Chinese students spend 15 to17 years study knowledge in school. So the school does not require students to research the new knowledge. They just need the student to memorize and calculate rather than to validate it that is correct.Just like the sky is blue. Why? Because our teacher is telling us the sky is blue. When people are very young, they do not know what many words mean. And the meaning of these words is also what other people give to it. After that their parents or teachers teach them what these words mean, because that knowledge is fixed and cannot be changed. The reality of the society requires people to not only to remember the knowledge, but also have to complete experiments. Solving the reality and ideal conflict can also make the education system more perfect.I agree with the author’s point that the students just use ways of dedication and obedience to answer the teachers’ question about knowledge. The teacher very easily controls and manages the students' learning progress, and can quickly lead students to think about the knowledge. They do not have a chance to choose the answers because teacher will give a correct answer when the student asks. There is nothing that can replace it. If the student does not use the correct answers to fill in the homework or exam problems, they won't get a good result, which has a great influence on their GPA.So that in the future they can't go to a good university. Therefore there are many schools that will provide opportunities for students and guidance to exercise to have a rich imagination. In China, many parents send their child to this school to exercise the ability before children go to the elementary school. Parents always are willing to provide their children with future security. People need the very rich and colorful thought from the children, because Children's thinking is not restricted and is not affected by the external environmental effects. Adult feeling and though t has a fixed pattern.And they also think things should be comprehensive and meticulous, they cannot do wayward things before they think. They need to have sense of responsibility and social moral consciousness, because they have more force of action and also have independent economic needs to support their actions. So the idea of children of the enlightenment, schools can compensate for these external factors, and reduce the bad influence of socially. So in conclusion I agree with Kie Hos’ ideas that people should cherish their children’s freedom to think, write and be creative in imagination, and make education system more perfect.He improves his idea on children thought, and uses his experiences to show other people what he thinks about the freedom of young people’s ideas. In return, I think that he demonstrated the ideas and perspectives made by the adults to reflect on their own ideas on the future of children’s thought, Children’s thought can help adults instead of limiting children’s development. The children’s thought is very rich and colorful, and they cannot be influenced by the adult’s thought. The adults will from their mind bring inspiration of the children. Do not imprison our thoughts. We can make our country perfect.

Smoke alarms Essay Example | Topics and Well Written Essays - 1000 words

Smoke alarms - Essay Example There is the need to look for ways of preventing and reducing the damages and deaths caused by fires in our homes. A smoke alarm is a device that can help in this fight by detecting the presence of smoke. The debate has however been on whether or not homeowners should install these devices. Homeowners should be required to install smoke alarms because they can save lives, help in protecting property, and the purchase of smoke alarms and reducing fires helps boost the economy. Discussion There a number of arguments against the use of smoke alarms in homes. First, it has been argued that many of the fire detectors in the market today are ineffective and are near useless. In an article written by Richard Patton (2010), the author argues that most of the deaths caused by fires are due to the inability of existing smoke alarms to relay alarms. For instance, he states that the ionization fire detector that has been marketed for more than forty years is defective and unreliable (Patton, 6). He argues that most of the smoke alarms in the market today endanger the lives of the users, and therefore should not be promoted for use in homes. He backs this claim by quoting a report by Gordon Vickery prepared in 1980 in which 50 million detectors were placed in buildings across America in a period of two years yet the fire loss and death rate went up in the same period (Patton, 6). However, Patton’s claim is not sufficiently convincing. Although some of the alarms in the market today might be ineffective, the solution lies in designing better alarms that have a better response. Furthermore, the study he is quoting to support this claim was conducted more than 30 years ago and it is likely that improvements have been made on these alarms. A related argument against the use of these alarms has been on the health risks they pose. In an article titled ‘the Potential Hazard of Ionizing Radiation in Smoke Detectors’ (2005) by Rosalie Bertell, the author states t hat ionizing smoke detectors have a radioactive component- Americium 241. This component has a half life of 458 years. It may be inhaled by the users as a result of the deterioration of the packaging of the detector when it is discarded in landfills. Therefore, having these detectors in our homes is likely to increase this threat, and the population may be exposed to diseases such as cancer and other genetic disorders. According to this article, this compound is absorbed in the body easily through the intestines or lungs. This is a major danger to the future generations, and therefore should not be used in our homes. The problem with this argument is that the author fails to explore the different safe options that can be used in disposing these detectors. Although they may have some form of radiation, proper disposals mechanisms can help eliminate this threat. In addition, the author does not clearly state the actual threat posed by these detectors. The arguments are not backed up w ith figures to illustrate this threat. The threat may not be significant after all. The use of these detectors cannot be trashed on the basis of the above claims since the benefits outweigh the costs by far. First, the purchase of smoke alarms and the reducing of fires is important to the growth of the economy. In a study conducted by Haddix et al (2001), the authors attempted to estimate the cost effectiveness of a smoke alarm giveaway program conducted in Oklahoma City. The results of the study showed that using these

Trading for Meatingly Essay Example | Topics and Well Written Essays - 3500 words

Trading for Meatingly - Essay Example It was 1985; I was 13 and had just beheld a goddess at the baseball card show. Looking back with the experience that years bring, I have often tried to unearth if she really was as beautiful as I first imagined, or if the impact of her appearance was simply some sort of ode to the relativity of all things. In essence, I have tried to discern if she really was as awesomely radiant in an absolute manner or if she appeared so simply because she was the only other girl of my age in the entire Ramada conference room that day. The crowd at baseball card shows in those days was predominately male and could be sorted into two general categories. First was the pre-to-young adolescent cohort. This was made-up of kids that were old enough to have some sort of job that provided income for their baseball card habit. They were also old enough to be trusted by parents to walk or ride a bike to the Ramada without stopping to take candy from strangers or getting into a rusty Dodge van with a man that promised to show you his pet turtle. We were a decidedly pimply lot with greasy hair, greasy smiles and pale skin from marathon baseball card trading sessions in basement entertainment rooms of friends and relatives. The second cohort was the gentlemen whose waist sizes were keeping pace with their age well into their late forties and early fifties. They were a beefy, jovial bunch of men that found great pleasure in statistics, speculation and talking with young adolescents for hours on end about baseball players. They never talked baseball. It was always the players. Like a secret language, the mention of certain surnames among these gentlemen could inspire awe and reverence or loathing and argument. Names from the recent past such as Yastremski and Morgan were invariably compared to older players such as Ruth and Young. Not just compared as players, but compared as commodities. This was the real love for these men. Who’s card would raise in value, fall in value? The future was the real interest for these men. Who was playing now that would be the next Ruth or Aaron? And more importantly, how can I get his cards cheap now so I can sell them at a profit in the future? So it is understandable why, given this backdrop of greasy, pimply, fleshy maleness, I might think that her beauty was somehow a mirage. How I might think she was the most beautiful girl simply because she was the only girl in the room at the time. For years, pondering on this first vision of her loveliness was one of my great pastimes. When I was too tired to pick up a book to read or simply didn’t want to invest the effort, I’d think about seeing her for the first time. Over time, I have come to believe that she was not lovely in relation to anything else, she simply was lovely. I now believe that had I seed her for the first time at poolside in the midst of a wild party full of gyrating, bikini-clad supermodels, her immaculate high-tops and ponytail would have had the exa ct same effect upon me. I would have forgotten my name, surreptitiously glanced her way at every opportunity and chiefly, nearly forgotten that I had embarked upon this particular trip to the card show on a special mission. I was, in fact, convinced that I had out speculated the men with the bellies. I was certain in 1985 that I had seen the future of baseball. I could see my fortune being made with a few purchases of a particular player.

Emotionally Intelligent leaders and their Impact on Followers Essay

Emotionally Intelligent leaders and their Impact on Followers - Essay Example Emotional intelligence comes closest to servant leadership style of management. A servant leader listens to his employees, takes feedback from them and looks to improve the overall conditions of the workplace. There is no blame put on individual employees and all the followers share work responsibility. Emotional intelligence can be measured by looking at the environment of the workplace. Based on the discussion above, a leader should be self-aware of himself and his employees. He should work for the benefit of his people. This would be evident from the response of people. If the leader is understanding, motivating and is trying to develop the social skills of his people then they will be happy. They will show more commitment towards work and the whole organization will prosper together. It is evident that employees prefer to work with emotionally intelligent leaders and they give their best efforts under him. In conclusion, emotional intelligence has great benefits for a leader as well as for employees. A leader knows what his followers want and try to make it available in the best possible way. There is peace as the leader is understanding and cooperative. The employees’ benefit as the leader constantly motivates them. They have a realistic goal to achieve which also seems fair to them. More importantly, they well recognized because the leader tries to listen to them by taking their feedback. This attribute in leaders helps to achieve company’s goals in less time as the employees feel contented to work.

Compare and contrast Assignment Example | Topics and Well Written Essays - 1000 words

Compare and contrast - Assignment Example Walter and Holden have very different living situations. Walter is a black man living in Chicago. He drives a limousine for a living. In the beginning, Walter, his wife, son, sister, and mother all live in a small apartment (Hansberry 23-24). Money is equated to happiness in Walter’s mind. He believes if he can finally make enough money all his problems would drift away. Money also equals manhood to Walter. He sees his sister’s friends George and Agasai as the future and the past. Agasai is the African root, whereas George is the future rich, assimilated, black man. Walter knew he needed change, but was unsure how to proceed. Holden, on the other hand, is a white student. He lives in the New York City area. Holden has an older brother, younger sister, and younger brother that died. Holden loves his little sister. He does have roommates, friends, and acquaintances, but cannot really relate to his peers and superiors. During the course of the story, Holden is trying to fi nd himself. He wants to explore his sexuality, personality, and life. Like Walter, Holden wanted change, but was unsure how to proceed. Walter and Holden had more differences than just their situation. Walter was in his 30’s, whereas Holden was a teenager. Walter is very secure in his sexuality. â€Å"Holden is a rebel and all that -- "the most terrific liar you ever saw in your life," "probably the biggest sex maniac you ever saw" -- but he's a softy at heart. He's always pitying people† (Yardley C01).Where Holden understands sexuality norms; he is still uncomfortable with losing his virginity. Walter is married with a son, but Holden is single with not children. Walter is not as well read as Holden. Holden only likes to read, but the rest of his academics are less than stellar (Salinger 24). Walter works, whereas Holden is a student. These are some of the major differences between Walter and Holden. Despite Walter and Holden’s differences, there are many simil arities as well. The similarities are more internal. Both Walter and Holden have dreams. These two characters try to achieve their dreams and goals, but do not want to put forth much of an effort. Walter and Holden do have definite opinions about their peers. Both men are trying to fit into the world and be respected. Walter’s dreams are about being rich. All of his problems would be gone with money. His marriage would be perfect. Walter’s family would be happy. All of his dreams are initially wrapped up in money. Despite dreaming about being rich, Walter does not want to work hard to achieve his goals. â€Å"Walter has many dreams but no plans to make them happen. Walter is obsessed with his dreams. They consume him to the point where he can't really see straight. He believes that everyone should see his way of thinking, and doesn't consider that it's his dream that may not be entirely clear. He'd rather do a get rich quick scheme. He is passionate and ambitious but incredibly irresponsible and childish. Poverty keeps him down but his inability to live in the real world also keeps him down. He's unable to move forward. He wants a world of luxury, immediately without work. He thinks he works hard enough at his ordinary job as a chauffeur† (Price). As a result of not wanting to work, Walter cooks up wild schemes. One wild scheme is to own a liquor store (Hansberry 33). Once Walter gives the money for the store, his friends rip him off.

Action to Transform Health Care Assignment Example | Topics and Well Written Essays - 3750 words

Action to Transform Health Care - Assignment Example Additionally, educational background along with lower income level of this segment of Montreal population often compels the indigenous groups to avail equal health care services. In this regard, a series of suggestive actions have been formulated that can increase the health care efficiency of the nursing institutions to protect health and wellbeing of the aboriginal members in the community. In this regard, changing and maintaining adequate compliance with the participation and accession of health care services can improve their process of protecting the wellness of the aboriginal groups. Furthermore, making continuous promotion of the health care facilities designed for the aboriginal groups along with improving the way of rehabilitation programs can also improve the current nursing trend in Montreal for the indigenous groups. In relation to the recent health care sector in Canada, a major development can be witnessed in terms of maintaining status and legitimacy in nursing of the community members. However, the health care sector of the nation is often alleged in terms of overlooking of conducting appropriate health and social care activities for the members especially the urban aboriginal groups. The aboriginal groups in the nations are subjected to face major disparities in terms of availing appropriate care, awareness and wellness programs to improve their health and wellbeing within the communities. Keeping with the changing notion in nursing practices, the primary objective of this research study is to bring a major understanding of the current nursing practice in Montreal Quebec, Canada. In this regard, the discussion of the report critically analyses discourses within the community regarding the status and legitimacy of aboriginals in the nursing sector. In addition, the discussion also tends to p rovide relevance suggestive actions that could

Partnership and collaboration in the promotion of child development Essay

Partnership and collaboration in the promotion of child development - Essay Example When looking at Louisa and James’ family, it can be seen that interactions and finding solutions for various situations can change the overall development of all the children. The scenario that requires specific actions is with Serena and the current situation that she has created with both school and personal development. Scenario of Serena Serena is known as a scholarly student in school and is continuously performing to have average to good marks in school. However, Serena’s personal relationships have recently altered. Serena is a daughter from Louisa’s previous marriage with her birth father, Colin. While Louisa has been in a relationship with James since Serena since she was one years of age, there are different dynamics from the previous relationship. Serena first met her father when she was six months old; however, the interactions were limited. Six months ago, Serena’s birth father, Colin, began to move into more contact with Serena. There have be en several interactions between the two in the past few months. The teachers and administration at the school have noted that in the same few months, Serena is beginning to alter with her studies. Her attendance has altered and she is withdrawn when she is in the classroom, as opposed to having the regular interactions and alertness that was noted from her past behaviours. There may be several reasons associated with this, all which are leading to different behaviours among Serena. The problem that has compounded is one which is directly linked to personal relationships; however, the interference with Serena’s school work is leading to new concerns among individuals and professionals. Providing Integrated Services from Children’s Services The problem that has arisen with Serena is one which requires integrated services to work effectively. The relationship is the basis of this; however, the effects which are occurring with school work are creating alterations in how th e main problem can be approached. The integrated services include the family that is involved in the relationship. It also includes professionals that are working within the school as well as counsellors who may be able to assist Serena to become more alert in school and to separate the personal relationships from the interferences that are occurring in the school (Parton, 976: 2006). For this to work effectively, the integration of the various team members will need to work together with the proper communication and understanding of the complete situation. Protocols and documentation will need to be used to follow with the right communication so the team members can work on the activities on hand while minimizing tensions between the professionals. The inter-personal and professional communication needs to be developed first, specifically which can provide better integrated services for Serena’s situation (Anning, 90: 2006). The two concepts which the integrated services wil l need to use are intervention and protection services. If this is done earlier, than the team will be able to stop any hindrances which may drastically affect Serena’s attendance as well as the potentially hazardous relationship that is affecting her school work. For the integrated services to work, the team defined will first need to define what interventions need to occur (Sloper, 571: 2004). The most well – known factor that is altering with Serena is her attendance and the school work that she is

Hemophilia Summary Essay Example for Free

Hemophilia Summary Essay Background -Hemophilia A is an inherited disorder in which one of the proteins needed to form blood clots is missing or reduced. This lacking protein is known as blood clotting factor 8. Without F8, the blood cannot clot properly to stop bleeding and can result in excessive bleeding or disabilities. Hemophilia A -When blood is not able to clot and allow wounds to heal, this is a result of Hemophilia A Symptoms Include: -Prolonged bleeding from cuts -Excessive nose bleeds -Many large bruisings -1 in 5,000 males are affected Blood Coagulation -Blood coagulation is the defensive process that causes blood to clot and helps prevent excessive blood loss when blood vessels are injured. -Coagulation is a complex process that involves 20 to 30 components, called blood coagulation factors, and a series of complex chemical reactions. -When a blood vessel is injured, platelets in the area of the damage clump together and stick to the edges of the cut to begin the coagulation process. -Platelets are fragments of cells containing clotting factors and play a major role in blood clotting. -These clotting factors help platelets stick together and activate fibrin. (These clotting factors combine with a protein called prothrombin in a reaction that converts prothrombin to thrombin. Thrombin then converts fibrinogen (a protein present in plasma) into long, sticky threads of another protein called fibrin) -The fibrin forms a mesh-like net over the opening and traps red blood cells as they try to leak out of the cut. -As the clot hardens, it forms a protective seal over the cut so that the injury can heal and the vessel wall can be restored. Factor 8 -One specific intrinsic clotting cofactor that stabilizes the fibrin clot is Factor 8. -F8 is activated by thrombin in the presence and is a cofactor in the activation of factor X (WHAT DOES X DO) -Ultimately Factor F8 cross-links fibrin polymers solidifying the clot. -Without this coagulation factor, vessels are not able to heal and therefore result in excessive bleeding (also known as Hemophilia A) Causes of F8 deficiency -Numerous mutations in the gene structure have been discovered. -Genetic abnormalities include genetic deletions of variable size, abnormalities with stop codons, and frame-shift defects. -Data suggest that 45% of severe hemophilia A cases result from an inversion mutation. F8 Gene -the F8 gene is located in the proximal part of chromosome X and is expressed in human liver, spleen, lymph nodes, and a variety of other tissues, -It’s one of the largest genes; it is 186 kilobases (kb) long and has a 9-kb coding region that contains 26 exons and 25 introns. -The shaded green region to a full blue and incomplete red displays that the gene gets transcribed into mRNA but not translated into proteins. Shaded green is the 5 and 3 untranslated regions that are able to bind to something else. -variant (1) consists of 26 exons and encodes the full-length isoform (a) -variant (2) contains an unique 5 exon located within intron 22 of transcript variant 1 Crystal Structure Is composed of a Ca Ion, Cu Ion, Alpha-D-Mannose N-Acetyl-D-Glucoamine. (Find out the importance/functions of these..?) Arrows = beta sheets Coils = alpha helix -how the F8 factor is incorporated / works in the overall protein. -responsible for generating the larger amounts of Xa and thrombin required for clot formation. -Covalent cross-linking of fibrin polymers by activated factor XIII (XIIIa) is required for adequate clot strength and normal wound healing. -How it works: catalyzes a transglutamination reaction that initially cross-links the C-terminal ends of the g chains on adjacent fibrin monomers. Intrinsic / Extrinsic It turns out that you actually need both the intrinsic and extrinsic pathways in your body. In a test tube, you can form fibrin along either pathway. But in the body, the pathways are intertwined in such a way that if you’re missing something on either the extrinsic or intrinsic side, you won’t be able to clot properly. In our bodies, the thing that kicks off the clotting cascade is tissue factor â€Å"exposure.† Tissue factor is not floating around in the blood normally – or at least, it isn’t normally â€Å"visible† to the blood (it might be in little membrane fragments, but it’s not active until it’s needed). When you need to form a clot, tissue factor appears, and together with factor VIIa (which happens to be just floating around in the blood) it converts factor X to Xa (which then converts prothrombin to thrombin, which converts fibrinogen to fibrin). So: clotting initially begins along the extrinsic pathway. The weird thing, though, is that as soon as we make a little Xa, that Xa (along with the aptly-named tissue factor pathway inhibitor) turns off the extrinsic pathway! A little thrombin is formed, though, before the pathway gets turned off – and that thrombin kicks off the intrinsic pathway (the other side of the cascade, with factors VIII and IX). Fibrin formation then proceeds along this pathway until it’s no longer needed. The bottom line is: you need both the intrinsic and extrinsic pathways to form fibrin in vivo. If you don’t have factors VIII or IX, you can’t utilize the intrinsic pathway – and you’ll have a very hard time forming fibrin! Intrinsic / Extrinsic Include the two different pathways that lead to the formation of a fibrin clot: the intrinsic and extrinsic pathway. Although they are initiated by distinct mechanisms, the two converge on a common pathway that leads to clot formation. Both pathways are complex and involve numerous different proteins termed clotting factors.

Smoking, Alcohol and Obesity in New Zealand

Smoking, Alcohol and Obesity in New Zealand Introduction This research project is going to deal with three kinds of Maori trends, which have been issued from 1919 to the present and this research is going to identify and demonstrate about Smoking, Alcohol and Obesity. Those trends based on Northland, New Zealand. Additionally, each trend is identified by each difference question. Below question of bullet points demonstrate what this research project is going to do. Smoking: Why do Maori women smoke during pregnant? Alcohol: Why do young Maori people drink alcohol? Obesity: Why do Maori people have obesity? Those above questions are going to be shown by ethical and cultural considerations as following methodologies, which are literature review and statistical data and graph. Moreover, those trends are approached to Maori Hauora form, which is Te Whare Tapa Wha and the form consider Taha Tinana (Physical health), Taha wairua (spiritual health), Taha wanau (family health), Taha hinengaro (mental health). For three Maori health trends, this research is going to involve health services which are accessibility and Affordability. Accessibility is that many Maori have issues on transport such as own car and transportation. Affordability is significant barrier for Maori to access general practitioner due to too high cost. Methodology -Literature Review Literature review has plenty of sources for this research project. The example of resources is book, Internet, journals, government publications, dissertations, theses, electronic databases and reference materials. Those resources are helpful to understand and identify 3 Maori trends that I choose in existing knowledge. By using those resources even literature review makes the research project to avoid reinventing the wheel by undertaking research for which the conclusions are already known. -Statistical data and Graph Statistical data and graph provide factual data which is based on true events that is occurred in the past, thereby we can identify Maori trends. Additionally, those methodologies make this research easy to gather information and analysing trends. à ¢- Literature Review Smoking: Question1. Why do Maori women smoke during pregnant? As national hospital data from 1999-2003, 39 percent of Maori women over 15 years old smoked during pregnant. On the other hands, 12.5 percent of non-Maori women over 15 years old smoked during pregnant. Even though Maori women had higher percent of smoking rate during pregnant, they tried to cut smoking for being safe of their baby. Below table is shown how many Maori women were quit smoking for pregnant. Table 1. Smoking rate broken into age of Maori women Below bullets are shown why they keep smoking during pregnancy. Nicotine is addictive; Study participants smoked on average 9 cigarette per day even 52 percent participants smoked within 30 minutes of waking. The women are healthy; The Maori women have not had experience health problems regarding with smoking. So, their motivation to quit is for baby. Poor knowledge of increased risk; Maori pregnant women have poor knowledge of increased risk. So, they do not know what kind of effect baby is affected by smoking. For helping explanation, below table is shown. Table2. Belief statement about smoking during pregnancy There are not may support agencies to help Maori pregnant women. 82% of women recall being advised to stop smoking but few health professionals provided cessation assistance or referral. The delivered information was mixed; some women also felt supported to just cut down and were told not to quit as withdrawals could stress the baby. The most significant reason why women keep smoking during pregnant is because most women tried to quit with 2 weeks of finding out they were pregnant but only 2 pregnancies were planned for pregnant and on average women did not know they were pregnant until 7-8weeks even they do not make a book with Midwife until 11-13 weeks. They are surrounded by smokers; 62% of Maori population smoked. 67% of partners smoked. So, pregnant women can access easily in smoking area. Below table is shown environment. Table3. Environment – a) Social and b) Work Alcohol: Question2. Why do young Maori drink alcohol? Alcohol is widely used by youth of Maori. There were 1702 Maori students in the Youth’07 sample accounting for 18.7% of the total secondary school sample. 43.5% of all Maori students perceived that it was okay for people their age to drink alcohol regularly. Maori students think drinking alcohol was okay because 78% of their friends regularly drank alcohol. Additionally, 66% of students’ parents drank alcohol regularly at home. So, Maori students thought it was okay for them and below figure 1 is shown where Maori students get their alcohol from. Figure1. Percentage of source The most common problems associated with drinking alcohol were doing things that could have got them into serious trouble that is reported by 28% of current drinkers and getting injured after drinking alcohol (27%). 34% of all Maori students reported that within the previous month they had been a passenger in a car with a driver who had been drinking alcohol. Of those Maori students who had driven on a public road, 15% reported that they had driven a car after consuming alcohol. Additionally, drinking alcohol has affected in diverse way following bullet point will show. Increased risks of motor vehicle collisions, injuries and deaths Increased risks of crime Increased risks of sexual risk taking Mental health problems and suicidal behaviours Below figure 2 is shown that problems associated with alcohol use among current drinkers. Figure2. Problems associated with alcohol use among current drinkers Three of problem associated with alcohol use are noticeable which are had unsafe sex, done things that could have got you into serious trouble and been injured after you had been drinking alcohol. Diabetes Question3. Why is Maori higher rate of diabetes? There is variety reasons that make diabetes occurred and obesity is the most affected occurring obesity among diverse reasons. Below figure and table are going to show how many Maori population is obesity as dividing ethnic group. Figure3. Proportion of the population aged 15+ who are obese, by sex ethnic group Table4. Obesity prevalence rate, Maori, Non-Maori, 1998/1990, 1997 There are many Maori suffering diabetes and the population having diabetes in Maori are much higher than non-Maori. The population is nearly three times more common in Maori. Additionally, Maori being diagnosed have type 2 diabetes which are expected to significantly increase over the next 20 years with the biggest impact being on Maori, Pacific people and those living in deprived neighbourhoods. The main reason that many Maori are having type 2 diabetes is unequal access to and quality of diabetes care. Although there may be many other reasons to explain disparities of death and complications from type 2 diabetes, there is evidence that ethnic in access to and quality of care may play a role. Table5. Type 2 diabetes mellitus, deaths (2000-2004) and hospitalizations (2003-2005) by ethnicity and sex Maori age being diagnosed of type 2 diabetes are 47.8years, six years younger than non-Maori(54.2years) and the self-reported prevalence of diabetes was 3.5 times higher among Maori than among non-Maori and besides the risk for hospitalization because of type 2 diabetes is 4 times higher for Maori than non-Maori as above table4. Diabetes has a tendency to bring other diseases. By doing this, diabetic complications are suffered that is renal failure, lower limb amputation, eyes problems and heart disease. Even those diabetic complications are diagnosed more for Maori than non-Maori. Prevention of diabetes at a community level is predicated upon promotion of healthy diet, exercise and thus, weight control. However, policy and practice strongly believe behaviour change at the individual level is significant. It is unfortunately that this is going to solve diabetic epidemic and structural change at the level of taxation incentive, food regulation and advertising for healthy changes in manufacturing will be needed. Ngati Porou Hauora (NPH) on the East Coast is implementing a programme called Ngati and Healthy. Their purpose is reducing the risk of type 2 diabetes mellitus by promoting a lifestyle characterised by healthy eating and regular exercise and also increase awareness of diabetes and pre-diabetic conditions both amongst those at high risk of developing diabetes. Analysis By using those above literature review, this research was demonstrated three Hauora trends which are smoking, alcohol and diabetes based on question. In addition, the information of data in literature review is going to be analysed with bullet points. Smoking: why do Maori women smoke during pregnant? High percentage of Maori women smoke during pregnant Having poor knowledge of increased risks for baby. Pregnant women have know well 3 problems that is out of ten problems, which are low birth baby, breathing problems and sickness in infant and sudden infant death syndrome. Not enough support agencies to help Maori pregnant women Difficult environment to cease smoking at home and working place. There are many people smoke surroundings pregnant women. Being ware of pregnant late cause unplanned pregnant. Pregnant women recognise after 2 weeks. The delivered information was mixed Alcohol: why do young Maori drink alcohol? Having easy environment to drink alcohol by family and friends Not being ware of drink alcohol Nearly half percentage of Maori students perceived that alcohol use is okay 78% of Maori students friends regularly drink alcohol 66% of parents of Maori student regularly drink alcohol Most Maori students take alcohol by friends and parents. 28% of current drinker get into them serious trouble 27% of current drinker are getting injured after drinking 34% of all Maori students reported that within the previous month they had been a passenger in a car with a driver who had been drinking alcohol Drinking alcohol has affected in mental health problems and suicidal behaviours Diabetes: why is Maori higher rate of diabetes? Common disease in Maori population Three times higher than non- Maori population for Maori Type 2 diabetes expected to significantly increase over next 20 years Having unequal access to Maori for quality of diabetes care Diabetic complications are diagnosed more for Maori which are renal failure, lower limb amputation, eyes problems and heart disease. Significant treatment is weigh control NPH (Ngati Porou Hauora) is implement for promoting promoting a lifestyle characterised Conclusion This research dealt three Hauora trends from 1919 to this present day regarding each questions. In the smoking part, many pregnant Maori women smoke during pregnancy. So, they need to support to cease smoking by education. As the research dealt, many pregnant Maori women have poor knowledge what side effect coming when they smoke during pregnant. This is most significant issues and other important issue is unplanned pregnancy. Therefore, they smoke until they recognise they are pregnant. To prevent this kind of happening, health provider have to deliver information to Maori female even male also to make them aware of side effect of smoking surrounding pregnant women. In the Alcohol part, Most Maori students are exposure to easily get alcohol and most significant problems is Maori students is not aware of seriousness of drinking alcohol because of their surroundings. Alcohol use make problems in variety situation and it make Maori students injured even seriously. So, to prevent this k ind of situation, they need to be provided education. In diabetes part, type 2 diabetes is common disease among Maori even that disease is occurred three times higher than non-Maori. The reason that diabetes is occurred is closely relative with lifestyle and the rate of obesity is higher than non-Maori. So, Maori need to improve their life style by exercise, control weight and manage diet. References Health Quality Safety Commission New Zealand, University of Auckland Lessons from research with Maori Women(2006), Retrieved from http://www.hqsc.govt.nz/assets/CYMRC/Resources/RSP-Maori-Women-Smoking.pdf New Zealand medical Association, The New Zealand Medical Journal, Why Maori women continue to smoke while pregnant, Marewa Glover, Anette Kira(n/d), Retrieved from http://www.whakawhetu.co.nz/sites/default/files/why%20maori%20women%20continue%20to%20smoke.pdf Heath Promotion Agency, Alcohol Use and Maori Young People (2007), Retrieved from http://www.alcohol.org.nz/sites/default/files/researchpublications/pdfs/AlcoholENGLISHFact_Sheett_08LoRes.pdf The New Zealand Medical Journal, Binge drinking among Maori secondary school students in New Zealand: association with source, exposure and perception of alcohol use (2013), Retrieved from https://www.nzma.org.nz/journal/read-the-journal/all-issues/2010-2019/2013/vol-126-no-1370/article-clark University OTAGO. 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